**autoloot should be enabled for everything but cards, (?very low rate drops?), and mvp drops. Its only for rare drops that the competition to grab the item and factors like looters become meaningful. for common drops disabling autoloot just leads to unhappy-carpal-tunnel-players. Double KO and getting the items is also kindof lame, I believe there is a setting to stop this.
**multiclienting takes away from the game, in that you must have (and be able to have) 5 clients open to compete. also when everyone has their own buffslave, why play a support character? nobody needs you, and greatly detracts from the social/community aspect.
to counter this, you could have an npc give all the buffs you could ever need. however this tends to throw off the game balance, and doesnt work well if you factor in certain buffs like soul link and gospel. its better instead to debuff when entering pvp/battlegrounds areas, and restrict warpers to dungeon entrances- if you ever have free warpers at all!
anti-multiclient hex cannot be relied upon: even if you have some arcane software that checks clientside and hasnt been bypassed, someone could just have 2 RO installs on their computer etc. ip restrictions are no good, because some people share ips and you want these people in your community (college students, family members, etc...). So- its best to have the server check for multiclients based on MAC address- at least then people won't have 10 clients open on one computer. have a banker for the zeny transfer issue, or better yet just make the zeny one value shared by all characters on the same account. stopping multiclient this way is also is just another layer to help deal with the possibility of botting as well.